一抗
二抗
亲和凝胶及免疫磁珠
蛋白质定量试剂盒
蛋白质
规格：
查看说明书| Product Name: | TIMP1 Mouse Monoclonal Antibody |
| Cat No.: | 2228 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IP |
| Recommended Dilution: | WB: 1:1000-2000; IP: 3ug/Sample |
| Format: | Liquid |
| Source: | Mouse |
| Purification Method: | Protein A/G Purified |
| Isotype: | IgG2a |
| Conjugate: | Unconjugated |
| Storage: | Store at -20℃. Do not aliquot |
| Immunogen: | Full length human TIMP1 protein |
| Full Name: | TIMP1 |
| Calculated Molecular Weight: | 25kDa |
| Observed Molecular Weight: | 27kDa+54kDa |
| Gene ID (NCBI): | 2228 |
| Background: | TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1 |
| Category: | Primary Ab |
引用文献
