Cat No.: D-AB-10161L

规格：

Product Name:	AMPK alpha2 Polyclonal Antibody
Cat No.:	D-AB-10161L
Clonality:	Polyclonal
Species Reactivity:	Human,Mouse,Rat
Tested Applications:	WB,IHC,IF
Recommended Dilution:	WB 1:500-1:1000,IHC 1:100-1:200,IF 1:100-1:400
Format:	Liquid
Source:	Rabbit
Purification Method:	Antigen Affinity Purification
Isotype:	IgG
Conjugate:	Unconjugated
Storage:	Store at -20℃. Avoid freeze / thaw cycles.
Immunogen:	Recombinant Rat Ampk2 protein expressed by E.coli
Calculated Molecular Weight:	62 kDa
Observed Molecular Weight:	62 kDa
Gene ID (NCBI):	78975
Background:	The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Category:	Primary Ab

引用文献