一抗
二抗
亲和凝胶及免疫磁珠
蛋白质定量试剂盒
蛋白质
规格：
查看说明书| Product Name: | CD59 Polyclonal Antibody |
| Cat No.: | D-AB-10258L |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB 1:500-1:1000 IHC 1:250-1:500 |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Antigen Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
| Immunogen: | Recombinant Human CD59 protein expressed by E.coli |
| Calculated Molecular Weight: | 14kDa |
| Observed Molecular Weight: | 14-17kDa |
| Background: | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. |
| Category: | Primary Ab |
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