Cat No.: D-AB-10194L

规格：

Product Name:	P38 Polyclonal Antibody
Cat No.:	D-AB-10194L
Clonality:	Polyclonal
Species Reactivity:	Human,Mouse
Tested Applications:	WB,IF
Recommended Dilution:	WB 1:500-1:1000, IF 1：50-1：200
Format:	Liquid
Source:	Rabbit
Purification Method:	Antigen Affinity Purification
Isotype:	IgG
Conjugate:	Unconjugated
Storage:	Store at -20℃. Avoid freeze / thaw cycles.
Immunogen:	Recombinant Mouse Mapk14 protein expressed by E.coli
Calculated Molecular Weight:	41kDa
Observed Molecular Weight:	41kDa
Background:	MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
Category:	Primary Ab

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