武汉戴安生物技术有限公司

3081  Caspase-1 Rabbit Polyclonal  Antibody

发表时间:2018-12-26 10:00

Cat#: 3081    Caspase-1Rabbit Polyclonal Antibody  

Only For Research.  Not For Diagnosis.                                                                                           查看PDF

Synonyms:

caspase a

Attribute:

Rabbit  Polyclonal  Antibody

Isotype:

Polyclonal

Purity:

Antigen Affinity Purification

Application:

ELISA, WB, IP

Calculated MW:


Observed MW:

10+20+30+44kda

Reactivity

Zebra fish

Immunogen

Peptide corresponding  to zebra fish caspase-1

Buffer

PBS with 0.1% sodium azide and 50% glycerol,  pH 7.2

Storage:

Store at -20.  Do not aliquot

Recommended Dilution:

WB: 1:1000-2000

IP: 1:5000-10000

IF: 1:100-200

Background

CASP1(caspase-1)  is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It  is a cysteine protease that regulates inflammatory processes through its  capacity to process and activate the interleukin-1-beta (IL1B), IL18, and  IL33 precursor proteins. The active caspase-1 can increase cellular membrane  permeability and intracellular calcium levels, which facilitates lysosome  exocytosis and release of host antimicrobial factors and microbial products


                                                                          3081 CASPASE1.png

                                                                            Western blot of Zebra Fishwhole lysates

                                                                             with anti-Caspase-1Rabbit Polyclonal  

                                                                             Antibodyat dilution of 1:1000





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