武汉戴安生物技术有限公司

3090  MAA/MDA Lysine Rabbit PAb (赖氨酸丙二醛乙醛化兔多抗)

发表时间:2018-12-25 16:58

                                                                                        图标2.jpg 赖氨酸丙二醛乙醛化兔多抗说明书‍

Cat#:3090   MAA Lysine Rabbit Polyclonal   Antibody


OnlyFor Research.   Not For Diagnosis                                              



Attribute:

Rabbit   Polyclonal Antibody

Isotype:

IgG

Purity:

Antigen Affinity Purification

Application:

WB, IP, ELISA

Reactivity

MAA aducts

Immunogen

MAA protein

Buffer

PBS with 0.1% sodium azide and 50% glycerol,   pH 7.2

Storage:

Store at -20.   Do not aliquot

Recommended Dilution:

WB: 1:1000-2000

IP: 1:5000-10000

Background

Malondialdehyde   (MDA) and acetaldehyde (AA) react synergistically to form hybrid   malondialdehyde–acetaldehyde (MAA) adducts . MAA adducts are unique among   aldehyde–protein adducts in their stability, potent immunogenicity, ability   to alter protein regulatory elements (i.e.,ε-amino lysine residue), and   dose-dependent direct cellular toxicity . These properties of MAA adducts   represent one pathogenic mechanism by which classical risk factors for   cardiovascular disease(i.e., hypertension, hyperlipidemia, diabetes, and   tobacco use) may result in inflammation and lead to specific clinical   entities such as atherosclerosis.


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