武汉戴安生物技术有限公司

3089  Succinylad Lysine Rabbit PAb(赖氨酸琥珀酰化兔多抗)

发表时间:2018-12-25 16:57

                                   图标2.jpg赖氨酸琥珀酰化兔多抗说明书


Cat#:3089    Succinylated Lysine Rabbit Polyclonal Antibody


Only For Research.   Not For Diagnosis.                                                                              

Attribute:

Rabbit   Polyclonal Antibody

Isotype:

IgG

Purity:

Antigen Affinity Purification

Application:

WB, IP, ELISA

Reactivity

Succinylated Protein

Immunogen

Succinylated BSA

Buffer

PBS with 0.1% sodium azide and 50% glycerol,   pH 7.2

Storage:

Store at -20.   Do not aliquot

Recommended Dilution:

WB: 1:1000-2000

IP: 1:5000-10000

Background

Succinylation   is a posttranslational modification where a succinyl group (-CO-CH2-CH2-CO2H)   is added to a lysine residue of a protein molecule. This modification is   found in many proteins, including histones. The potential role of   succinylation is under investigation, but as addition of succinyl group   changes lysine's charge from +1 to −1 (at physiological pH) and introduces a   relatively large structural moiety (100 Da), bigger than acetylation (42 Da)   or methylation (14 Da), it is expected to lead to more significant changes in   protein structure and function. By analogy to acetylation, it has been   suggested that succinyl-CoA is the cofactor of enzyme-mediated lysine   succinylation.

                                   

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